ADALTA LIMITED

AdAlta Limited develops next-generation protein and cell therapies—including innovative treatments for cancer and fibrosis—using its proprietary i-body platform inspired by shark antibodies, bridging Asian immunotherapy advances with Western clinical markets. One

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About ADALTA LIMITED (ASX:1AD)

AdAlta Limited is a clinical-stage biotechnology company based in Melbourne, Australia, dedicated to developing next-generation cell and protein therapeutics for serious and hard-to-treat diseases, particularly solid cancers and fibrotic conditions. Central to AdAlta’s innovation is its proprietary **i-body platform**, a unique technology inspired by the antigen-binding domain of shark antibodies, enabling the discovery and development of novel medicines with improved specificity and stability compared to traditional antibodies. This platform allows AdAlta to create targeted protein therapeutics addressing significant unmet medical needs.

The company’s primary strategy, termed “East to West,” leverages Asian advances in T-cell therapy and integrates them with the robust clinical and manufacturing efficiencies of the Australian ecosystem. Through this approach, AdAlta aims to bridge innovative cellular immunotherapies from Eastern markets with regulatory pathways and patient populations in Western markets. This positions AdAlta as a global conduit, accelerating the translation of cutting-edge cancer immunotherapies into clinically approved treatments and ensuring faster, broader patient access.

AdAlta has already made significant progress with its drug candidate **AD-214**, developed as an innovative treatment for fibrotic diseases. While seeking strategic and financial partners to advance AD-214 into Phase II trials, the company continues to expand its research and clinical pipeline. Ultimately, AdAlta is focused on monetizing its R&D achievements and establishing itself as a leader in both protein and cell therapy therapeutics for life-threatening diseases.

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